International Journal of Medical Science and Dental Research

Current Issue Volume 6 Issue 1 (January 2023)

    • Comparative Evaluation of Some Liver Enzymes in Preeclamptic and Non-Preeclamptic Patients in the Enugu Metropolis South East Nigeria
      Preeclampsia (PE) is one of the most common causes of maternal mortality and morbidity. It complicates 3-6% of all pregnancies globally and up to 15% of pregnancies in the Sub-Saharan Africa. The present study was designed to determine the level of liver enzymes in preeclamptic patients compared to control in the Enugu metropolis. A total of 70 subjects comprising 35 preeclamptic patients and 35 non-preeclamptic controls aged 18-40years were recruited for the study. Blood samples (10ml) were collected from subjects for estimation of liver enzymes involving the Alanine Transaminase (ALT), Aspartate Transaminase (AST) and Alkaline Phosphatase (ALP) levels using Randox Kit, UK.The data was analyzed using T-test and Pearson correlation. The level of significance was set at p<0.05. The result revealed significant increase in ALT (57.70+28.72 vs14.19+2.96Iu/L), AST (42.54+8.66 vs 10.5+3.801u/L) and ALP (380.12+15+62 vs 174.14+46.531u/L) between the preeclamptic and non-preeclamptic subjects. There was a significant positive association of the ALT (p=0.031 vs 0.700) and AST (p=0.02 vs 0.222) with the systolic blood pressure between the preeclamptic and non-preeclamptic subjects as well as the ALT(p=0.011 vs 0.106) and AST(p=0.003 vs 0.225) with the diastolic blood pressure between the preeclamptic and non-preeclamptic subjects. These findings provides scientific evidence for the management of the adverse outcomes of preeclampsia in our population.

      Keywords:: Preeclampsia, Liver enzymes, Enugu Metropolis.

    • The Effectiveness of Web Base Programs on the Reduction of Obesity among Adults at Makkah Al-Mukarramah, 2022. Experimental Study
      Background:Individual behavioral habits that contribute to overweight and obesity include a poor diet and a lack of physical activity. These are linked to more diseases, a worse quality of life, early weakness, and higher mortality. Individualized web-based therapies show promise in changing behavior and achieving successful weight loss at a low cost. The long-term implications, however, have not yet been fully examined. Aim: The aim of the study was to investigate the effects of regular attendance in a 12-week web-based weight loss program. Setting: The study was carried out in PHCS. at Makkah. Research Design: Experimental study used a pragmatic approach, with enrollment and outcomes assessment being exclusively online. Subject: After randomization, they attended the first medical examination and the second after completing the 12-week weight loss program. N = 50 of the intervention. Results: Regarding the number of hours of sleep, there is no significant differences between before and after web base programs on the reduction of obesity; related to the amount of water you drink per day there is statistically significant differences between before and after web base programs on the reduction of obesity. There are statistically significant differences before and after participants’ dietary intakes from baseline to 12 weeks with full-fat milk, low or skimmed milk, Fish and Brown bread, fruits, Vegetables, Fruit juices, Soft drinks, Desserts (cake - cookies...), French fries, or chips and fast food (p= <0.001*). Recommendation: should be enhanced web-based program features, such as personalized feedback, is required to determine what features are necessary to elicit and support individuals to positively change their eating habits.

      Keywords:: Web base programs, Reduction of obesity.

      • The Level of Knowledge and Determinants of Children’s Developmental Milestones From Birth to 36 Months Among Mothers Attending Well-Baby Clinic at Al-Eskan Primary Health Care Center in Makkah Al-Mukarramah, 2018
        Aim: To evaluate the level of knowledge and the determinants about the children’s developmental milestones among mothers. Methodology: An observational cross-sectional study on 197 mothers attending the Well-Baby Clinic with their children at Al-Eskan primary health care center. Data were collected using the Caregiver Knowledge of Child Development Inventory. Results: The main sources of mothers’ knowledge about children’s developmental milestones were their family/friends, internet and social media. About half of mothers had poor knowledge regarding general knowledge about developmental milestones. Non-Saudi mothers had poorer knowledge regarding cognitive and socialemotional development of infants than Saudi mothers p<0.05. Mothers with lowest education had significantly poorest knowledge. Unemployed mothers had significantly poorer knowledge regarding cognitive and socialemotional development of toddlers than employed mothers p<0.02. Mothers with low educational status had significantly poorer knowledge regarding gross and fine motor development of children than employed mothers p<0.05. Younger mothers had significantly poorer general knowledge regarding developmental milestones of children p<0.05. Non-Saudi mothers had significantly poorer general knowledge than Saudi mothers p<0.05. Mothers with low education had significantly poorer general knowledge p<0.001. Unemployed mothers had significantly poorer general knowledge than employed mothers p<0.02. Conclusions: Mothers’ knowledge about developmental milestones is suboptimal. Their main sources of information are family/friends, internet. Younger, non-Saudi, less educated, and unemployed mothers have less knowledge than older, Saudi, more educated and employed ones.

        Keywords:: Developmental milestones, mothers’ knowledge, primary health care, well-baby clinic.

        • Clinical Evaluation of Retreatment of Endodonticaly Treated Teeth with two Different Rotary File System
          Aim: The aim of this clinical study was to evaluate and compare the intensity of postoperative pain after root canal retreatment with two different rotary file systems.
          Methodology: Patients for root canal retreatment were assigned to one of the two retreatment file system groups (HyflexEDM and Neoendo retreatment file). The gutta percha from obturated canal was removed. The working length was determined to be 1 mm shorterthan the ‘0.0’ mark of the apex locator. Root canals were filled with gutta-percha and an epoxy resin-based root canal sealer using a lateral compaction technique. The teeth were restored using a resin composite material. A single operator performed the retreatments in a single visit.Participants were asked to rate the incidence and intensity of the postoperative pain on a verbal rating scale 24, 48, and 72 hours after treatment. Also,if any analgesic tablets were taken, the number is noted.
          Conclusion: Both the retreatment file system performed similarly after retreatment in endodontically treated teeth.

          Keywords:: Hyflex EDM, Neo endo retreatment file, Post operative pain.