International Journal of Medical Science and Dental Research

Current Issue Volume 3 Issue 5 (November 2020)

    • Chronic Granulomatous Disease in Libya
      Chronic granulomatous disease (CGD) is a rare inherited disorder of the innate immune system, characterized by a greatly increased susceptibility to severe infections, early in childhood at different sites. We aimed to study multisystem clinical manifestations of CGD in Libyan children. Our study was retrospective, it included CGD patients seen at Pediatric hospital immunology department in Benghazi, over 7 years. Out of 35 CGD patients, 66% was males, 94% had onset of disease <1 year of life, and 60% of their parents were relatives. Reticuloendothelial system was involved in 94% followed by skin (91%), respiratory (83%), gastrointestine (69%) and bone (29%). This study is one of the largest series on CGD from north Africa and Arabic region reflecting the different modes of inheritance, as well as the wide and variable clinical manifestations of CGD.

      • Wastewater-based epidemiology in coping with COVID-19 in Brazil: implications for Primary Health Care actions as an alternative for community monitoring and diagnosis Abstract:
        The wastewater-based epidemiology could subsidize regional actions to contain the SARS-CoV-2 in Primary Health Care (PHC), allowing anticipating the mobilization of services in areas of potential risk. With the information from the sewers, PHC services could organize interventions considering local specificities, in order to enhance their attributes. Sewage Epidemiology would allow being able to monitor spatial and temporal trends, produce results in near-real time (through biosensors), generate information on a population scale, and determine the status of COVID-19 within and among communities. In addition, it would require less public spending compared to clinical testing. Even with the limitations on the optimal coverage of sanitation services in all cities, Sewage emerges as another point to be considered at this pandemic time, presenting itself as a tool that can provide a collective diagnosis in the communities, adding to the strengthening of health, epidemiological and environmental surveillance systems in the country.

        Keywords: COVID-19; SARS-CoV-2; Wastewater-Based Epidemiological Monitoring; Primary Health Care.

        • The Vital Roles of Tele dentistry during the Current Situation of COVID-19 Pandemic ABSTRACT:
          Dentistry involves routine close face-to-face interaction with patients, and during the COVID-19 pandemic, it has mostly been suspended. Teledentistry can offer an innovative solution to resume dental practics during this pandemic. In this review, we provide a brief overview of applications of teledentistry. Articles on teledentistry, relevant to this review, were searched and consulted from PubMed, Google Scholar, and Cochrane database. Teledentistry is the remote facilitating of dental treatment, guidance, and education via the use of information technology instead of direct face-to-face contact with patients. Teleconsultation, telediagnosis, teletriage, and telemonitoring are subunits of teledentistry that have important functions relevant to dental practice. There are many challenges for acceptance of teledentistry by the dentists as well as patients, which need to be addressed urgently. This review concludes that teledentistry can make it easier to connect dental practices with outreach programs; this allows dental practice to engage in social responsibility and community services. In addition to outreach, dental professionals can improve their practice by enhancing relationships with specialists and consultants as they engage with them more efficiently, and may connect them to the patients when necessary.

          Keywords: Teledentistry, Telehealth, Telemedicine, COVID-19, Coronavirus

          • Antioxidant Activity, Toxicity Effect and Phytochemical Screening of Some Brown Algae Padina australis Extracts from Dutungan Island of South Sulawesi Indonesia ABSTRACT:
            Brown algae is one of the bioactive compound sources producing secondary metabolites as antioxidant. Padina australis is a brown algae (Phaeophyceae) specific in Dutungan island Barru, South Sulawesi suspected of secondary metabolic compound. This study aims to determine the level of toxicity and antioxidant active compounds of Padina australis. Extraction of active compounds in P.australis was carried out by maceration method using a solven of methanol, ethyl acetate, and n-hexane. Each extract was tested for its toxicity against Artemia salina L and DPPH as radicals. The results showed that the toxicity test of methanol, ethyl acetate, and n-hexane extract against A. salina L obtained LC50 values, respectively 785.03 ppm, 73.3 ppm and 300 ppm. Antioxidant activity of methanol, ethyl acetate and n-hexane extract with IC50 values at 446.88 ppm, 259.48 ppm, and 495.67 ppm.

            Keywords: Antioxidant, Toxicity, P.australis, Brown algae, Phytochemical screening