International Journal of Medical Science and Dental Research

Current Issue Volume 4 Issue 6 (November-December 2021)

    • Leptine and its Participation in the Development of Obesity
      Background: Obesity is a chronic, multifactorial disease that increases significantly in the world population, affecting both adults and children and adolescents. In addition, it can lead to developing other diseases. Leptin is a hormone that is produced in various tissues of the body, adipose tissue being the protagonist in this pathology; giving it great relevance in terms of its participation as a producer of substances that make it an active tissue.
      Methodology: A narrative review was carried out, in which different databases were used, in English and Spanish languages, obtaining a total of 21 articles, 15 of which met the inclusion criteria.
      Results: Obesity is generated due to an energy imbalance, between caloric intake and expenditure. Likewise, leptin varies, according to its intravascular concentration, it modulates food consumption, responding to fasting states and the presence of glucose, so that when a deficit of this occurs, obesity can arise either in isolation or in concomitance with other factors that also induce its development.
      Conclusions: Leptin is a hormone that is produced in adipose tissue, which has various functions in the body. It is currently known to play an important role in the development of obesity. However, its mechanism of action must be further studied and elucidated so that as a drug many more results can be generated in favor of the treatment of this pathology.

      Keywords:: Leptin, obesity, metabolism, adipose

  • The Use of Monolithic Zirconia Restorations for Patients with Bruxism
    Patients with bruxism develop wear of occlusal surfaces of teeth, which may require an extensive rehabilitation. The treatment planning criteria for patients with bruxism involve a wide range of materials and procedures. Introduction of monolithic zirconia ceramics (second generation of zirconia) opened a wide range of full ceramic applications. In fact, monolithic zirconia has a better translucency and preserve adequate strength and toughness. Its lower Alumina content optimally distributed within the material helps maintaining aging stability. Our goal is to give an overview of different properties of monolithic zirconia and its use to treat patients with bruxism.

    Keywords:: zirconia, monolithic zirconia restorations, bruxism, full ceramic

  • Soft Tissue Analysis of Chin in Patients with Different Mandibular Divergent Patterns in Himachali Population
    Abstract:Introduction : The soft tissue of the face plays an important role in facial esthetics. Lower third of the face constitutes the lips and the chin throat region and has a unique impact on the facial dynamics. With continuing growth, the chin tends to assume forward position relative to the superior aspects of the skeletal face and the mandible grows from the more retruded to a less retruded position.. Objective : Determination of STC thickness and its relation with mandibular divergence. Material and Methods: Pretreatment lateral cephalograms of 150 subjects (80males 70 females) aged 18–45 years. On basis of mandibular plane angle 4 groups, Low angle, Medium-Low, Medium-High, High angle were formed. The STC thickness was measured at 3 levels: Pog-Pog', Gn-Gn', Me-Me'. Results:The analysis of variance and post-hoc test were also used to compare the studied parameters separately among groups. the STC was more in males. STC thickness was greater in the low-angle group, and gradually decreases across groups, the least being in the high-angle group.Conclusion: The STC thickness was more in men as comapared to females,STC measurements were less in patients with vertical hyperdivergent pattern and thickness was significantly thinner at Me in cases of hyperdivergent pattern

    Keywords:: chin thickness, facial profile, lateral cephalogram, mandible, mandibular plane angle