Effect of Adding nano titanium Dioxide and Chitosan On Antibacterial, Water Sorption and Solubility of Glass Ionomer Cement
To evaluate the water sorption, solubility and antibacterial activity of glass ionomer cement incorporating nano-titanium dioxide as well as chitosan.
The samples were prepared in six groups, including non-modifed GIGs (NMGIC, n = 12), chitosan incorporated GICs (CHGIC, n = 12),3% nanotitanium incorporated GICs (nanoTio2GIC, n = 12), 5% nanotitanium incorporated GICs (nanoTio2GIC, n = 12), chitosan/3% nanotitanium incorporated GICs (CH/nanoTio2/GICs, n = 12),chitosan/5% nanotitanium incorporated GICs (CH/nanoTio2/GICs, n = 12) .The antibacterial activity was evaluated using a direct contact test against Streptococcus mutans. The water sorption and solubility of modified glass ionomer cement were evaluated. Data were analyzed using the ANOVA and Tukey tests. Statistical significance was set at the 0.05 probability level.
With the dual-modification, a significant improvement in the antibacterial properties was found.However, no difference was found in water sorption.
Under the limitations of the present investigation, the following conclusion can be drawn:5% wt TiO2 NP modified GIC powder with the chitosan modified GIC liquid (Group 5) exhibited the highest antibacterial activity against S. mutans.