International Journal of Medical Science and Dental Research

Volume 5 Issue 4 (July-August 2022)

    • Chronic Tibial Osteomyelitis; Use of Biactive Glass as an Alternative of Treatment. Report of a Case
      Chronic osteomyelitis is a disease usually of infectious origin. The main cause is post-traumatic, it affects the bone tissue and surrounding tissue, the most frequent causative agent is Staphylococcus aureus. The most affected bone is the tibia. Case description: A 42-year-old male with a diagnosis of chronic tibia osteomyelitis, with sequelae of previous surgical interventions, multiple antibiotic treatments, and type IV B classification by Cierny-Mader. Methods: Two-stage surgical management was chosen. Firstly, extensive bone and soft tissue debridement, placement of cement beads medicated with amikacin in the medullary cavity and osteoclast system for irrigation with vancomycin. In the second stage, free fibular bone grafting, fixation and stabilization with screws, bioactive glass placement in areas of interface between stabilized fibula and posterior tibial cortex. Results: Before a multitratada chronic osteomyelitis it is necessary to individualize and evaluate treatment alternatives, in this case the surgical management in two time, the use of medication beads, bone graft and the use of bioactive glass, achieved a complete eradication of the infection and favorable clinical evolution with optimal functional recovery of affected limb.

      Keywords:: Chronic osteomyelitis, Tibia, Bioactive glass.

      • Influence of bone marrow-derived mesenchymal stem cells versus low-level laser irradiation therapy on the rat parotid glands after streptozotocin- induced diabetes
        Objective: The current study was designed to assess the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSCs) versus low-level laser therapy (LLLT) on the rat parotid glands after streptozotocin induced diabetes in rats. Materials and Methods: 48 Sprague-Dawley rats were divided into 4 groups, 12 rats each. Group I: the animals received 0.1 M sodium citrate buffer intraperitoneally, the vehicle of streptozotocin. Group II: diabetes mellitus was induced by single intraperitoneal injection of 60 mg/kg of streptozotocin (STZ) dissolved in 0.1 M sodium citrate buffer. Group III: one day after diabetes induction, single dose of 2×106 BMSCs suspended in 0.5 ml of phosphate buffer solution (PBS) was injected via intraglandular route. Group IV: one day after diabetes induction; the animals were exposed to single session of LLLT on the right parotid gland area. Animals were sacrificed at 7 or 14 days after BMSCs injection or laser irradiation parotid glands were harvested, then histological and immunohistochemical studies were performed. Result: The experimental stem cell treated group showed better histological features and more PCNA proliferation than the laser treated group. Conclusion: bone marrow derived stem cell and laser treatment are successful method in the treatment of diabetic induced salivary gland injury, with relative superiority of stem cell treatment.

        Keywords:: Parotid gland, stem cells, laser- therapy, diabetes

        • Purple Sweet Potato Biscuits Affects Total Antioxidant Levels in Pregnant Women with Anemia
          Background: One of the causes of the high maternal mortality rate is anemia that occurs during pregnancy. The purpose of this study was to determine the effect of giving eel and purple sweet potato biscuits to total antioxidant levels in anemic pregnant women in the Pampang Public Health Center, Makassar City. Research methods: This study used experimental research methods with a Randomized Control Trial pretest-posttest design with a control group. The research was conducted in the working area of Pampang Public Health Center, Makassar City. The number of samples was 20 pregnant women who were divided into 2 groups, namely the control group and the comparison group. The data analysis used included Wilcoxon, Mann Whitney, Paired T-test, and Independent T-test. Research result. The results: of the Mann Whitney test showed that there was no significant effect on the total antioxidant levels of pregnant women between groups in the post-intervention condition (p=0.496>0.05). However, the Wilcoxon test results showed a significant effect in both the intervention group (p=0.005) and the control group (0.018 <0.05). Conclusion: It was concluded that giving eel biscuits and purple sweet potato could increase total antioxidant levels and albumin levels in anemic pregnant women in the working area of Pampang Public Health Center Makassar City.

          Keywords:: Eel, Purple Sweet Potato, Total Antioxidant, Albumin

          • Is Using Wire and Screw Technique Aid Reduction during Open Treatment of Condylar and Subcondylar Fractures
            Objectives: To evaluate the use of wire and screw technique to aid reduction during open treatment of condylar and subcondylar fractures. Methods: This study consisted of 10 patients divided into two groups, (five for each group). First group, the reduction was assisted through the use of (6 mm length - 2 mm diameter) screw, 26-gauge stainless steel wire, and 16-gauge needle. Second group, the reduction was performed using a towel clip and bone hook without stripping the lateral pterygoid muscle from its condylar insertion. The time of operation was calculated and clinical evaluation of complications had been done for both groups. Computed Tomography (CT) was taken to confirm the position of the reduced condylar fractures. Results: All fractures had reduced into their normal position without developing series of complications in the 6-month follow-up period. Conclusion: Using wire and screw technique for reduction of subcondylar fractures during the open treatment gives the surgeon the ability to move the fractured mandible as a bony anchorage through the reduction screw with minimal or no postoperative complications related to that technique of reduction

            Keywords:: Open reduction, wire and screw technique, condylar fracture

            • A Case of Metastatic Breast Cancer Treated Successfully by Using Yoga Prana Vidya (YPV) Healing Methods Persistently As Complementary Medicine and Patient’s Self-Belief
              Introduction: Breast cancer is diagnosed mostly in women, and recent research shows Breast Cancer in India accounted for 13.5% of all cancer cases and 10.6% of all deaths. Breast Cancer originates when breast cells mutate and lose control on their division leading to a mass of tissue called tumor. Treatment options include multidisciplinary approaches. This paper presents a case of metastatic breast cancer of a 49-year-old female treated successfully by Yoga Prana Vidya healing protocols as complementary medicine. Method: This paper uses case study method of investigating the case, going through details of medical reports, YPV healers’ documents, and patient feedback. Results: The patient started taking YPV healings from August, 2020, while simultaneously taking medical treatment. Slowly and gradually through persistent healings, meditations, rhythmic breathing, forgiveness Sadhana and learning lessons over the course of two years, the patient began to recover from April-May 2022 onwards. Active cancer cells in the breast, quantum of pain, dependency on pain killers and radiation therapy have substantially reduced after healings. Conclusions: Breast cancer is one of the most common diseases after skin cancer diagnosed in women, and early detection methods and personalized treatment approaches are saving lives. Yoga Prana Vidya has been established as a complementary and also as alternative medicine to successfully treat a variety of conditions, as seen in this case. Further research using YPV as complementary medicine with appropriate number of samples of cases similar to this case is recommended to throw more light on treatment and normalization of this condition.

              Keywords:: Yoga Prana Vidya System ®, YPV ®, Breast Cancer, Tumor, Chemotherapy, complementary and alternative medicine.

              • A Spectrophotometric assessment of Icon resin infiltration on the color of White Spot Lesions over one year (An In Vivo Study).
                Objective: The aim of this trial is to assessment of Icon resin infiltration on the color of White Spot Lesions (WSLs) over one year. Material and methods: 20 participants with 4 WSLs in their anterior teeth (total 80 WSLs) were enrolled in this study. The Icon resin infiltration was applied to WSLs according to the manufacturer’s instructions. The WSLs color change (ΔE) was Spectrophotometric assessed by Vita Easyshade V device at the following evaluation periods: before treatment (T0), immediately after treatment, (T1), 3-(T2), 6- (T3), and 12-months later (T4). Data were recorded and statistically analyzed. Results: There was a significant improvement in ΔE after immediate application and in all follow-up periods. However, there was a significant decrease in ΔE with time. Conclusion: The Icon resin infiltration technique is effective in WSLs esthetics improvement. However, Icon resin infiltrated WSLs may become discolored with time.

                Keywords:: Color stability, Esthetic improvement, Icon resin infiltration, White Spot Lesion.

                • Lower Protocol with Immediate Provisional Load: Clinical Case Report on Immediate Implants
                  Implantology started from the studies by Branemark who, through his research, concluded that the dental replacement procedure could be done through two stages, one surgical with the placement of implants and another prosthetic (Brånemark et al., 1969). The classical technique indicated the beginning of the prosthetic phase only 6 months after implant placement (Albrektsson et al., 1986), but over time, this technique underwent changes and improvements. In order to successfully install these implants, several factors are necessary, including primary stability. This can be defined by the primary fixation that the implant receives when it is inserted into the bone bed after the perforations made by drills containing at least 32 Ncm of locking (Ottoni et al., 2005) One of these improvements was the immediate loading of implants, implant with primary stability and provisional prosthesis without osseointegration having occurred (Manfrinato et al., 2021). For this to occur, the procedure in question has to be performed in a period between 1 to 20 days (Nishioka SR et al., 2003). This causes the number of clinical sessions with the patient to decrease, in addition to guaranteeing function and aesthetics to the patient (Pereira et al., 2007).

                  • The Effect of Extract of U. Pilulifera on Some Kidney Parameters of Diabetic Rats
                    Diabetes is associated with health impacts and several organs are negatively affected by diabetes including kidneys. Various herbal remedies have been used to treat diabetes. U. pilulifera is one of herbal treatments for diabetes. The main objective of the present study is to investigate the therapeutic potential of U. pilulifera in offering kidney protection through assessment of urea, uric acid and creatinine. Methodology included collection of U. pilulifera and preparation of its extracts, induction of diabetic model and biochemical evaluation of urea, uric acid and creatinine tests. Study findings showed that levels of urea, uric acid and creatinine were significantly increased in diabetic group (P <0.05). Therapeutic options using the extract of U. pilulifera were able to significantly decrease the levels of urea, uric acid, and creatine (P <0.05). Taken together, experimental diabetic model showed negative impacts on kidney function tests urea, uric acid and creatinine. Using the extract of U. pilulifera showed significant restoring ability to restore kidney function tests to levels approximate to reference range. Taken together, the extract of U. pilulifera has a potential therapeutic option to be used in diabetic patients with renal impacts.

                    Keywords:: diabetes, kidney function test, urea, uric acid, creatinine, U. pilulifera